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路上云

路上云
博士,副教授,碩士研究生導師
E-mail: lushangyun.sxmu@aliyun.com
教育經歷:
2016.9 – 2020.7中國農業大學,營養與食品安全專業,博士
2013.9 – 2016.7中國海洋大學,食品科學專業,碩士
2009.9 – 2013.7陜西師范大學,食品科學與工程專業,學士
工作經歷
2024.12-至今c7c7.app公共衛生學院,營養與食品衛生學教研室,副教授
2020.10-2024.12c7c7.app公共衛生學院,營養與食品衛生學教研室,講師
學術任職
山西省營養學會副秘書長
榮譽獲獎
2022年公共衛生學院中青年教師教學基本功競賽二等獎
教學情況
主要承擔本科生《預防醫學》、《營養與食品衛生學》課程,研究生《食物、營養與健康》課程;主持山西省高等學校教學改革創新項目1項(編號:J20230516)。
研究領域
營養與慢性疾病
代表性科研項目:
1.國家自然科學基金青年項目(編號:82304147),30萬元,主持,在研。
2.c7c7.app博士啟動基金(編號:XD2025),40萬元,主持,在研。
3.山西省應用基礎研究計劃青年項目(編號:202103021223215),5萬元,主持,已結題。
4.山西省教育廳高校科技創新計劃項目(編號:2021-224),3萬元,主持,已結題。
5.山西省博士啟動基金(編號:SD2016),5萬元,主持,已結題。
6.國家重點研發計劃項目子課題(編號:2018YFC1603005-1),230萬元,參與,已結題。
代表性論著:
1.Lu S, Xu Y, Zhang H, Liu Z, Xu J, Zheng B, Shi D, Qiu F. Glycyrol Relieves Ulcerative Colitis by Promoting the Fusion of ZO-1 with the Cell Membrane through the Enteric Glial Cells GDNF/RET Pathway. J Agric Food Chem. 2024 Jul 3;72(26):14653-14662. doi: 10.1021/acs.jafc.4c00239.
2.路上云,徐佳麗,許楊,等.甘草酚調節腸道菌群及其代謝產物激活自噬拮抗5-氟尿嘧啶致小鼠結腸損傷的機制研究[J].營養學報,2024,46(04):372-382.DOI:10.13325/j.cnki.acta.nutr.sin.20240801.001.
3.Lu S,Xu J,Xu Y, Liu Y, Shi D, Wang J, Qiu F. Glycyrol attenuates colon injury via promotion of SQSTM1/p62 ubiquitination and autophagy by inhibiting the ubiquitin-specific protease USP8, Journal of Functional Foods, 2023, 103.
4. Zhao S#,Lu S#,Fan L, Hu H*. Glycyrol Alone or in Combination with Gefitinib Is Effective against Gefitinib-Resistant HCC827GR Lung Cancer Cells, Applied Sciences-Basel, 2021, 11, 10526.
5.Lu S,Sun Z, Hu W, Yin S Yin S*, Zhao C, Hu H*. PD-L1 positively regulates MET phosphorylation through inhibiting PTP1B. Cancer Science, 2021, Doi: 10.1111/cas.14844.
6.Lu S,Liu S, Cui J, Liu X, Zhao C, Fan L, Yin S*, Hu H*. Combination of patulin and chlorpyrifos synergistically induces hepatotoxicity via inhibition of catalase activity and generation of reactive oxygen species. Journal of Agricultural and Food Chemistry. 2019, DOI:10.1021/acs.jafc.9b04814.
7.Lu S,Ye L, Yin S, Zhao C, Yan M, Liu X, Cui J, Hu H*. Glycyrol exerts potent therapeutic effect on lung cancer via directly inactivating T-LAK cell-originated protein kinase. Pharmacological Research. 2019,147:104366.
8.Lu S,Yin S, Zhao C, Fan L*, Hu H*. Synergistic anti-colon cancer effect of glycyrol and butyrate is associated with the enhanced activation of caspase-3 and structural features of glycyrol. Food and Chemical Toxicology. 2019, DOI: 10.1016/j.fct.2019.110952.
9.Lu S,Zuo T*. Effect of Food Additives on the Gut Microbiome in Relation to Human Health. Nutrition and Food Toxicology. 2018, 2(5):474-476.
10.Lu S,Zuo T, Zhang N, Shi H, Liu F, Wu J, Wang Y, Xue C, Tang Q*. High throughput sequencing analysis reveals amelioration of intestinal. dysbiosis by squid ink polysaccharide. Journal of Functional Foods, 2016, 20:506-515.
11.路上云,左濤,王江華,鄭榮,王玉明,薛長湖,唐慶娟*. 16S rDNA克隆文庫法分析兩種魷魚墨多糖對小鼠腸道菌群多樣性的影響[J].中國食品學報, 2016, 16(10):154-159.