尚紅園

臨床藥學教研室，講師，博士

E-mail: shanghongyuan@sxmu.edu.cn

教育經歷

2018年9月—2021年6月 蘇州大學，博士

2015年9月—2018年6月 c7c7.app大學，碩士

2011年9月—2015年6月 天津中醫藥大學，學士

工作經歷

2021年10月—至今 c7c7.app

教學情況

主講生物藥劑學、臨床藥物動力學、臨床藥學英語、臨床藥學實訓、新型藥物遞送技術、現代藥劑學。

研究領域

1、功能化納米材料的可控制備；2、生物小分子電化學傳感器。

代表性科研、教改項目

1、國家自然科學基金委員會, 面上項目, 52073199, MOF衍生的異質結中空納米材料的構筑及其在全水分解中的應用, 2021-01-01 至 2024-12-31, 59萬元, 資助期滿, 參與

2、山西省科學技術廳, 山西省青年科學研究項目, 202103021223217, 腫瘤微環境多重響應的銅基LDH納米編碼體系的構建及其外泌體診療一體化研究, 2022-01 至 2024-12, 5萬元, 在研, 主持

代表性論著

1、Q.F. Zhang, Z.L. Yang, C.M. Fan, G. Liu, F.S. Liu, H.Y. Shang*, Ru Atoms and Human Hemoglobin Confined in Nanoporous ZIF-67 as a Peroxidase-Mimicking Nanozyme for Cancer Identification. Acs Applied Nano Materials, 2025, 8(7), 3368-3377.

2、H.Y. Shang*, A.P. Zhang, X.F. Zhang, J.W. Du, R.P. Zhang, Ultralow Ru doping MOF-based sensing probe with interface engineering regulation-triggered detection of hydrogen sulfide and cystathionine γ-lyase activity. Sensors and Actuators B: Chemical, 2025, 426, 136978.

3、H.Y. Shang*, M.L. Ding, X.F. Zhang, A.P. Zhang, J.W. Du, R.P. Zhang, Ultrasensitive optical biosensing detection and multiple therapy based on an NIR-II thermoelectric nanoheterojunction. Chemical Engineering Journal, 2024. 499, 156392.

4、H.Y. Shang*, X.F. Zhang, M.L. Ding, A.P. Zhang, J.W. Du, R.P. Zhang, Smartphone Imaging Device for Multimodal Detection of Hydrogen Sulfide Using Cu-Doped MOF Sensors. ACS Appl Mater Interfaces, 2024, 16(24), 30890-30899.

5、A.X. Liu, W.F. Song, C. Zhang, H.Y. Shang*, Colorimetry/Smartphone Dual-Mode Sensing Platform Based on Nanorod-Shaped Ni-Fe MOFs for Ascorbic Acid Detection. ACS Applied Nano Materials, 2024, 7(11), 13400-13406.

6、H.Y. Shang*, X.F. Zhang, A.P. Zhang, J.W. Du, R.P. Zhang, Engineering electronic band structure of ternary thermoelectric nanocatalysts for highly efficient detection of hydrogen sulfide. Journal of Materials Chemistry A, 2024, 12(19), 11544-11550.

7、H.Y. Shang*, X. Dong, X.F. Zhang, A.P. Zhang, J.W. Du, Electrocatalytic-Induced Electrochemical Sensor Based on the Heterojunction Cu-Ni/Ni(OH)2 for the Detection of Hydrogen Sulfide. ACS Applied Nano Materials, 2023, 6(24), 23576-23584.

8、Q.F. Zhang, Z.L. Yang, H.T. Zhou, J.W. Du, H.Y. Shang*, Electrochemical sensor for hydrogen sulfide detection using electrocatalysis-assisted amplification and chemical reaction-mediated signal enhancement. Microchim Acta, 2023, 190(12), 474.

9、H.Y. Shang*, X.F. Zhang, M.L. Ding, A.P. Zhang, C. Wang, A smartphone-assisted colorimetric and photothermal probe for glutathione detection based on enhanced oxidase-mimic CoFeCe three-atom nanozyme in food. Food Chemistry, 2023, 423, 136296.

10、H.Y. Shang*, X.F. Zhang, M.L. Ding, A.P. Zhang, C. Wang, Dual-Mode Paper Biosensing Platform Based on Oxidase-Like CoFeMn Nanozymes for Point-of-Care Detection of Glutathione. ACS Applied Nano Materials, 2023, 6(10), 8907-8915.

11、H.Y. Shang*, X.F. Zhang, M.L. Ding, A.P. Zhang, Dual-mode biosensor platform based on synergistic effects of dual-functional hybrid nanomaterials. Talanta, 2023, 260, 124584.

12、H.Y. Shang*, M.L. Ding, X.F. Zhang, W. Zhang, Dual-mode biosensing platform for sensitive and portable detection of hydrogen sulfide based on cuprous oxide/gold/copper metal organic framework heterojunction. Journal of Colloid and Interface Science, 2023, 629, 796-804.

13、W. Zhang, M.L. Ding, X.F. Zhang, H.Y. Shang*, Biosynthesis-mediated Ni-Fe-Cu LDH-to-sulfides transformation enabling sensitive detection of endogenous hydrogen sulfide with dual-readout signals. Analytica Chimica Acta, 2022,1229, 340390.

14、Shang, H. Y.; Xu, H.; Jin, L. J.; Wang, C.; Chen, C. Y.; Song, T. X.; Du, Y. K., 3D ZnIn2S4 nanosheets decorated ZnCdS dodecahedral cages as multifunctional signal amplification matrix combined with electroactive/photoactive materials for dual mode electrochemical - photoelectrochemical detection of bovine hemoglobin. Biosens. Bioelectron. 2020, 159, 112202.

15、Shang, H. Y.; Xu, H.; Wang, C.; Jin, L. J.; Chen, C. Y.; Zhou, G. Y.; Wang, Y.; Du, Y. K., General synthesis of Pd-pm (pm = Ga, In, Sn, Pb, Bi) alloy nanosheet assemblies for advanced electrocatalysis. Nanoscale 2020, 12 (5), 3411-3417.

16、Shang, H. Y.; Xu, H.; Liu, Q. Y.; Du, Y. K., PdCu alloy nanosheets-constructed 3D flowers: New highly sensitive materials for H2S detection. Sens. Actuators B-Chem. 2019, 289, 260-268.

17、Shang, H. Y.; Xu, H.; Jin, L. J.; Chen, C. Y.; Song, T. X.; Wang, C.; Du, Y. K., Electrochemical-photoelectrochemical dual-mode sensing platform based on advanced Cu9S8/polypyrrole/ZIF-67 heterojunction nanohybrid for the robust and selective detection of hydrogen sulfide. Sens. Actuators B-Chem. 2019, 301, 127060.

18、Shang, H. Y.; Xu, H.; Jin, L. J.; Chen, C. Y.; Wang, C.; Song, T. X.; Du, Y. K., Three-dimensional palladium-rhodium nanosheet assemblies: Highly efficient catalysts for methanol electrooxidation. J. Colloid. Interf. Sci. 2019, 556, 360-365.

19、Shang, H. Y.; Han, D.; Ma, M.; Li, S.; Xue, W. T.; Zhang, A. P., Enhancement of the photokilling effect of TiO2 in photodynamic therapy by conjugating with reduced graphene oxide and its mechanism exploration. J. Photoch. Photobio. B 2017, 177, 112-123.