mail:wangzhenyu32@sxmu.edu.cn
教育經(jīng)歷
2019年9月—2022年12月 南京中醫(yī)藥大學(xué),博士
(中國科學(xué)院上海藥物研究所聯(lián)合培養(yǎng))
2015年9月—2018年7月 c7c7.app,碩士
2011年9月—2015年7月 c7c7.app,學(xué)士
工作經(jīng)歷
2025年8月—至今 c7c7.app藥學(xué)院 講師
2023年1月—2025年5月 中國科學(xué)院上海藥物研究所博士后
2019年4月—2019年9月 中國科學(xué)院上海藥物研究所 科研助理
2018年7月—2019年4月 c7c7.app第一醫(yī)院
研究領(lǐng)域
有機合成方法學(xué),包括過渡金屬催化的惰性化學(xué)鍵活化;過渡金屬催化的偶聯(lián)反應(yīng)等。
代表性科研、教改項目
1、2024-2025中國博士后科學(xué)基金面上項目(No.2024M753371) 8萬 主持/結(jié)題
2、2023-2025上海市“超級博士后”激勵計劃(No.2023706) 30萬 主持/結(jié)題
代表性論著
1、Zhen-Yu Wang, Xu Zhang, Wen-Qing Chen, Guo-Dong Sun, Xing Wang, Lin Tan, Hui Xu*, Hui-Xiong Dai*. Palladium-Catalyzed Deuteration of Arylketone Oxime Ethers.Angew. Chem. Int. Ed.2024,63, e202319773. (IF: 16.9,中科院一區(qū))
2、Zhen-Yu Wang, Huiying Xu, Xu Zhang, Xing Wang, Hui Xu*, Hui Gao*, Hui-Xiong Dai*. Dual ligands relay-promoted transformation of unstrained ketones to polyfluoroarenes and nitriles.Sci China Chem.2023,66, 2037-2045. (IF: 9.7,中科院一區(qū))
3、Zhen-Yu Wang, Yi Sun, Guo-Dong Sun, Hui Xu*, Hui-Xiong Dai*.Total Synthesis of Syringin and Its Natural Analogues via C—C Bond Activation of Aryl Ketones. Chin. J. Chem.2023, 41,3587-3592. (IF: 5.5,中科院一區(qū))
4、Zhen-Yu Wang, Biao Ma, Hui Xu,Hui-Xiong Dai*.Arylketones as Aryl Donors in Palladium-Catalyzed Suzuki–Miyaura Couplings.Org. Lett.2021, 23,8291?8295. (IF: 5.0,中科院一區(qū))
5、Zhen-Yu Wang,Hui-Xiong Dai*. Synthesis of Trifluoromethylarenes via Nickel-Mediated C-O Bond Activation of Phenol Derivatives.Chin. J. Org. Chem.2020,40, 3971-3972. (IF: 2.2,中科院三區(qū))
6、Zhen-Yu Wang, Shurong Ban*, Mengchen Yang, Qingshan Li*. Switching the Enantioselectivities in Michael Addition of Pyrazolin-5-Ones to Nitroolefins by Benzoylthiourea Organocatalysts.ChemistrySelect.2017,2, 3419–3422. (IF: 2.0,中科院四區(qū))
7、Zhen-Yu Wang, Shurong Ban*, Mengchen Yang, Qingshan Li*. Highly enantioselective Michael addition of cyclohexanone to nitroolefins catalyzed by pyrrolidine-based bifunctional benzoylthiourea in water.Chirality.2016,28, 721–727. (IF: 2.8,中科院三區(qū))
8、Xing Wang,Zhen-Yu Wang, Xu Zhang, Hui Xu*, Hui-Xiong Dai*.Construction of C(sp2)–Si Bonds via Ligand-Promoted C–C Bonds Cleavage of Unstrained Ketones. Org. Lett.2022, 24,7344-7349. (IF: 5.0,中科院一區(qū))
9、Xu Zhang,Zhen-Yu Wang, Xing Wang, Hui Xu*, Hui-Xiong Dai*. Functionalized styrene synthesis via palladium-catalyzed Csingle bondC cleavage of aryl ketones.Tetrahedron Letters,2022,95, 153721. (IF: 1.5,中科院四區(qū))
10、Xing Wang, Ling-Jun Li,Zhen-Yu Wang,Hui Xu*, Hui-Xiong Dai*. Homologation of aryl ketones to long-chain ketones and aldehydes via C–C bond cleavage.iScience.2022.25. 104505. (IF: 4.1,中科院二區(qū))
11、Mei-Ling Wang, Hui Xu, Han-Yuan Li, Biao Ma,Zhen-Yu Wang, Xing Wang,Hui-Xiong Dai*. Mizoroki–Heck Reaction of Unstrained Aryl Ketones via Ligand-Promoted C–C Bond Olefination.Org. Lett.2021,23,2147–2152.(IF: 5.0,中科院一區(qū))
12、Zi-Qiong Guo, Hui Xu, Xing Wang,Zhen-Yu Wang, Biao Ma, Hui-Xiong Dai*. C3-Arylation of indoles with aryl ketones via C–C/C–H activations.Chem. Commun., 2021,57, 9716-9719. (IF: 4.2,中科院二區(qū))
13、Han-Yuan Li, Biao Ma, Qi-Sheng Liu, Mei-Ling Wang,Zhen-Yu Wang, Hui Xu, Ling-Jun Li, Xing Wang, Hui-Xiong Dai*. Transformations of Aryl Ketones via Ligand-Promoted C?C Bond Activation.Angew. Chem. Int. Ed.2020,59, 14388–14393.(IF: 16.9,中科院一區(qū)top)
14、Hui Xu, Biao Ma, Zun-Yun Fu, Han-Yuan Li, Xing Wang,Zhen-Yu Wang, Ling-Jun Li, Mingyue Zheng, Hui-Xiong Dai*. Ligand-Promoted Alkynylation of Aryl Ketones: A Practical Tool for Structural Diversity in Drugs and Natural Products.ACS Catal.2021,11, 1758–1764. (IF: 13.1,中科院一區(qū))
15、Kai-Liang Tao, Xing Wang, Huan Liu, Wen-Qing Chen, Yi Sun, Yun-Qian Zhang, Yu-Xi Li,Zhen-Yu Wang, Yang Ye, Hui Xu, Lefu Lan,*Hui-Xiong Dai*. Multisite modifications of arenes using ketones as removable handles enabled by Pd and norbornene cooperative catalysisNature synthesis2024,4, 209–218.(IF: 20.0,中科院一區(qū))