姓名:崔香麗
性別:女
民族:漢
出生日期:1962.12
出生地:山西
通信地址:c7c7.app生理
學歷學位情況
職稱情況
學歷學位 畢業時間 畢業學校 專業 級別 聘任時間
本科： 1983.6 c7c7.app 化學 初級 1983.7
碩士： 1994.6 c7c7.app 生物化學 中級 1992.12
博士： 2002.6 c7c7.app 生理學 高級 1996.6
本 人 簡 歷
時間 單位 職務
1983.6～1992.12 c7c7.app 助教
1992.12～1996.6 c7c7.app 講師
1996.6～2002.6 c7c7.app 副教授
2002.6至今 c7c7.app 教授
2005.1～2011.5 Universityof South Carolina Research
科研項目：
1.白藜蘆醇通過改變miR-31-5p的表達抑制腸癌細胞增殖。山西省自然科學基金，201801D121311。崔香麗等
2.白藜蘆醇通過p53介導的CD4+/CD25-效應T細胞凋亡抑制結腸炎和結腸炎相關腸癌。國家自然科學基金，81272695。崔香麗，L.J Hofseth,孫要軍等
3.氨甲酰膽堿的正性肌力作用及其機制。山西省自然科學基金，20031101。崔香麗等
4. ß3-腎上腺素能受體在心衰中的表達及其作用。2012011040-8。崔香麗等
5.增強反向Na/Ca交換——提高心肌變力性的新途徑。國家自然科學基金。30170346.
2001.3.1-2003.12.吳博威，武冬梅，崔香麗，韓清華，張軒萍，郭永強
6.心肌細胞離子通道的生理藥理特性研究。2萬。c7c7.app博士啟動基金，200307。崔香麗，趙錄英，吳博威。
科研獲獎情況：
1.反向鈉鈣交換對正?：頭屎裥募∠赴謀淞π宰饔?012年山西省高等學校自然科學研究優秀成果（科學技術）二等獎，主持。
2.第一作者論文獲美國ARCC 2011年度”Most cited 2010 Papers”。
3.鈣增敏劑的正性變力作用及其作用機制：2005年山西省科學技術三等獎，第二參加人。
4.鈣增敏劑的正性變力作用及其作用機制：2005年山西省高等學校自然科學二等獎，第二參加人。
5.牛磺酸與氨氯吡咪合用抗缺血再灌注心肌損傷及心律失常研究，2003年山西省高等學?？萍冀蕉冉保諶渭尤?/p>
發表的科研論文：
Publications in English
通信作者：
1. Qianqian Zhao，Huanzhen Chen, Jiani Jing, Xi Wang, Rong Liu, Xiaopeng Li, Haiqing Li, Xiangli Cui*. Role of β3 adrenoceptor in rat thoracic aorta contractility. Int J Clin Exp Pathol 2017;10(9):9132-9145
2.Haiqing Li, Qianqian Zhao, Rong Liu, Lan Yang, Huanzhen Chen*, Xiangli Cui*. Protective effect and potential of mechanism of simvastatin on myocardial injury induced by diabetes with hypoglycemia.Exp Clin Endocrinol Diabetes.2018; 126(03): 148-161
3.趙倩倩，景佳妮，李海清，劉蓉，李曉鵬，崔香麗.β3-AR阻斷劑SR59230A對大鼠胸主動脈張力及microRNA表達的影響.中國應用生理學雜志, 2017,33(1):6-10
4.劉蓉，宛欣，王茜，李凡璐，景佳妮，崔香麗.siPGK1增加黑色素瘤細胞對Vemurafenib敏感性及其機制的初步探索.中國應用生理學雜志, 2017,33(4):289-293
5.景佳妮，李凡璐，宛欣，王茜，趙倩倩，崔香麗.SR 59230A對大鼠心臟microRNAs表達的影響.中國應用生理學雜志, 2017,33(5):456-460
6.王茜，張鈞棟，劉鑫，龐波，吳亞俐，李宇星，賈文靜，彭菁，崔香麗.白藜蘆醇通過G2期阻滯抑制結腸癌細胞的增殖. 中國中西醫結合消化雜志.2018,26(2):167-171
7.宛欣，王茜，李凡璐，吳亞俐，劉鑫，陳還珍，崔香麗.辛伐他汀對糖尿病大鼠腎臟細胞凋亡的影響研究.中國糖尿病雜志，2018, 26(9)：760-764
8.宛欣，王茜，李凡璐，吳亞俐，劉鑫，陳還珍，崔香麗.辛伐他汀對糖尿病大鼠腎臟的保護作用及其可能機制.中國應用生理學雜志,2018, 34(4): 313-317
9.李凡璐，宛欣，王茜，吳亞俐，劉鑫，陳還珍，崔香麗.辛伐他汀對糖尿病大鼠心臟炎癥反應的干預作用及可能機制.中國糖尿病雜志，2018,26（12）：1029-1034
10.李凡璐，宛欣，王茜，崔香麗.辛伐他汀通過抑制氧化應激防止糖尿病所致心肌細胞凋亡.中國應用生理學雜志,2018, 34（5）：422-426,469,后插4-后插5
11．吳亞俐，劉鑫，劉凱麗，崔香麗，王春芳.氯化兩面針堿對小鼠潰瘍性結腸炎的干預作用及其機制, 2019, 35(6):520-535,475
12.劉鑫，吳亞俐，劉凱麗，崔香麗，都新新，張文琴。白藜蘆醇對小鼠潰瘍性結腸炎的影響. 2019, 35(5)：447-453
13.劉凱麗，都新新，張文琴，吳亞俐，王茜，王春芳，崔香麗.過表達miR-31對結腸炎模型小鼠TLR4/NF-κB信號通路及凋亡蛋白的調控. 2020, 36(3)：211-215,239,后插1-后插3
第一作者，代表性論文：
1.Xiangli Cui, Erin E Witalison, et al.The Induction of microRNA-16 in Colon Cancer Cells by Protein Arginine Deiminase Inhibition Causes a p53-Dependent Cell Cycle Arrest.PLoS One. 2013; 8(1): e53791.
2.Xiangli Cui, Yu Jin, Udai P. Singh, et al. Suppression of DNA damage in human peripheral blood lymphocytes by a juice concentrate: A randomized, double-blind, placebo-controlled trial.Molecular Nutrition and Food Research. 2012;56(4):666-70.
3.Xiangli Cui, Yu Jin, Tia Davis, Anthony Windust, Mitzi Nagarkatti, Prakash Nagarkatti, and Lorne J. Hofseth. Mechanistic insight into the ability of American ginseng to suppress colon cancer associated with colitis.Carcinogenesis.2010.31(10):1734-41.
4.Xiangli Cui,Yu Jin, Anne B. Hofseth, Alexander Chumanevich, Mitzi Nagarkatti, Prakash S. Nagarkatti, Udai P. Singh, and Lorne J. Hofseth. Resveratrol suppresses colitis and colon cancer associated with colitis. Cancer Prevention Research. 2010. 3(4):549-559.（該論文獲美國ARCC 2011年度. Cancer Prevention Research引用率最高的文章之一）
5. Hristov Krill,Cui Xiangli(co-firstauthor), Brown Sean, et al. Stimulation of beta3-adrenoceptors relaxes rat urinary bladder smooth muscle via activation of the large-conductance Ca2+-activated K+ channels. Am J Physiol Cell Physiol. 2008. 295:C1344.9084-53.
6.Xiangli CUI,Huanzhen Chen, Bowei Wu. Carbachol exhibited positive inotropic effect in rat ventricular myocytes via M2muscarinic receptors. Acta Physiologica Sinica. 2007.59: 667-673
7.XiangliCui, Huanzhen Chen, Dongmei Wu, Bowei Wu.Carbachol augments Na/Ca exchange current via M2muscarinic receptors in guinea pig ventricular myocytes.Acta PhysiologicaSinica. 2004. 56: 713-716
8.Xiangli Cui, Huanzheng Chen, Dongmei Wu, Bowei Wu. Enhancement of Ca2+transients and contraction of single ventricular myocytes of rats by 5-(N,N-dimethyl) amiloride. Acta PhysiologicaSinica. 2002. 54: 219-224
9.XiangliCui, Luying Zhao, Bowei Wu. E-4031 enhanced Ca2+transient and ventricular myocytes contraction via reverse mode Na+/Ca2+exchange in normal and hypertrophic rats. Acta Pharmacologica Sinica. 2002. 23: 797-802.
第二/其它SCI作者：
1. Erin E Witalison, Xiangli Cui, Anne B. Hofseth, Venkataraman Subramanian, Corey P. Causey, Paul R. Thompson, Lorne J Hofseth. Inhibiting Protein Arginine Deiminases Has Antioxidant Consequences.J Pharmacol Exp Ther.2015. 353(1): 64-70. doi: 10.1124/jpet.115.222745.
2. Erin E Witalison, Xiangli Cui, Corey P. Causey, Paul R. Thompson, Lorne J Hofseth. Molecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancer.Oncotarget.2015. 3;6(34):36053-62. doi: 10.18632/oncotarget.5937.
3. Deepak Poudyal, Xiangli Cui, Phuong Mai Le, TiaDavis, Anne B. Hofseth,Yu Jin, AlexanderA. Chumanevich, Michael J. Wargovich, MitziNagarkatti, PrakashS.Nagarkatti, Anthony Windust, and LorneJ. Hofseth.A limited role of p53 on the ability of a Hexane fraction of American ginseng to suppress mouse colitis.J Biomed Biotechnol. 2012;2012:785739. doi: 10.1155/2012/785739 :
4. Deepak Poudyal,Xiangli Cui,Phuong Mai Le, Anne B. Hofseth, Anthony Windust, Mitzi Nagarkatti, Prakash S. Nagarkatti, Aaron J. Schetter, Curtis C. Harris, Lorne J. Hofseth. A key role of microRNA-29b for the suppression of colon cancer cell migration by American ginseng. Plos
One. 2013. 8(10): e75034
5.Kevin L. Bicker, Lynne Anguish, Alexander A. Chumanevich, Michael D. Cameron, Xiangli Cui, Erin Witalison, Venkataraman Subramanian, Xuesen Zhang, Alena P. Chumanevich, Lorne J. Hofseth, Scott A. Coonrod, and Paul R. Thompson. D-Amino Acid-Based Protein Arginine Deiminase Inhibitors: Synthesis, Pharmacokinetics, and in Cellulo Efficacy. ACS Med Chem Lett. 2012. 26; 3(12):1081-1085.
6. Yu Jin,Xiangli Cui, Udai P. Singh, Alexander A. Chumanevich, Brook Harmon, Philip Cavicchia, Anne B. Hofseth, Venkata Kotakadi, Brandy Stroud, Suresh R Volate, Thomas G. Hurley, James R. Hebert, Lorne J. Hofseth. Systemic inflammatory load in humans is suppressed by consumption of two formulations of dried, encapsulated juice concentrate. Mol Nutrition & Food Research. 2010. 54(10):1506-1514.
7.Alexander A. Chumanevich, Deepak Poudyal,Xiangli Cui,Tia Davis, Patricia A.
Wood, Charles D. Smith, and Lorne J. Hofseth. Suppression of colitis-driven colon cancer by a novel small molecule inhibitor of sphingosine kinase.Carcinogenesis. 2010.31(10):1787-93.
8.Yu Jin, Anne B. Hofseth,Xiangli Cui, Anthony J. Windust, Alex A. Chumanevich, Lydia E. Matesic, Narendra P. Singh, Mitzi Nagarkatti, Prakash S. Nagarkatti, Lorne J. Hofseth. American ginseng suppresses colitis through p53 mediated apoptosis of inflammatory cells.Cancer Prevention Research.2010. 3:339-347
9. Katsuhiko Yoshizawa, Elena Jelezcova, Ashley R. Brown, Julie F. Foley, Abraham Nyska,Xiangli Cui,Lorne J. Hofseth, Robert M. Maronpot, Samuel H. Wilson, Antonia R. Sepulveda, Robert W. Sobol. Gastrointestinal Hyperplasia with Altered Expression of DNA Polymerase ß. Public Library of Science. 2009. 4: e6493
10. Yu Jin, Venkata S. Kotakadi, Lei Ying, Anne B. Hofseth,Xiangli Cui, Patricia A. Wood, Anthony Windust, Lydia E. Matesic, Edsel A. Pena, Codruta Chiuzan, Narendra P. Singh, Mitzi Nagarkatti, Prakash S. Nagarkatti, Michael J. Wargovich and Lorne J. Hofseth. American ginseng suppresses inflammation and DNA damage associated with mouse colitis. 2008. Carcinogenesis. 29:2351-2359
11. Venkata S.Kotakadiy, Yu Jin, Anne B.Hofseth, Lei Ying,Xiangli Cui,Suresh Volate, Alexander Chumanevich, Patricia A.Wood, Robert L.Price, Anna McNeal, Udai P.Singh, Narendra P.Singh, Mitzi Nagarkatti, Prakash S.Nagarkatti, Lydia E.Matesic, Karine Auclair, Michael J.Wargovich5 and Lorne J.Hofseth. Ginkgo biloba extract EGb 761 has anti-inflammatory properties and ameliorates colitis in mice by driving effector T cell apoptosis. Carcinogenesis. 2008. 29: 1799–1806, 2008
12. Desuo Wang,Xiangli Cui. Evaluation of PDE4 inhibition for COPD. International Journal of COPD. International Journal of COPD. 2006: I(4) 373-379
13. Huachen Zhao, Zhongbao Liu, Qilong Feng,Xiangli Cui, Bowei Wu. Effects of neuropeptide Y on ion channels in ventricular myocytes. Acta Physiologica Sinica. 2006; 58: 225-231
14. Huanzheng Chen,Xiangli Cui, Wenling Guo, et al. Positive inotropic effect of MCI-154 on hypertrophied heart of rats and its mechanism. Chinese Journal of Pharmacology and toxicology. 2004, 18: 338-343
15. Huachen Zhao, Dongmei Wu,Xiangli Cui, Bowei Wu. Enhancement of sodium-calcium exchange induces positive inotropic action and potentiates ouabain effect. Acta Physiologica Sinica. 2004. 56: 476-480
16. Huanzhen Chen,Xiangli Cui, Huachen Zhao, Luying Zhao, Jiyuan Lu, Bowei Wu. Inotropic effects of MCI-154 on rat cardiac myocytes. Acta Physiologica Sinica. 2004; 56: 301-305
Abstracts：
1.Xiangli Cui, Kiril L Hristov, Whitney F Kellett, Sean M Brown, Georgi V Petkov.Stimulation of β3–adrenoceptors activates spontaneous transient outward BK currentsand causes relaxation in rat urinary bladder smooth muscle. 2008 Annual Experimental Biology meeting, (April 5-9, 2008), San Diego, CA, USA.
The FASEB Journal.2008;22:1201.18
2.Xiangli Cui, Kiril L Hristov, Sean M Brown, Georgi V. Petkov.Stimulation of β3–adrenoceptors with BRL 37344 relaxes rat urinary bladder smooth muscle via activation of large conductance Ca2+-activated K+(BK) channels. 2008 Annual Biophysical Society Meeting, February 2-6, 2008, Long Beach, CA, USA.B397.
3.KrillLHristov,Xiangli Cui, Whitney F Kellett, Eric Rovner, Georgi V Petkov. Evidence for the presence of large conductance Ca2+-activated K+channels in native human urinary bladder smooth muscle. 2008 American Urological Society Annual Meeting, May 17-22, Orlando, FL, USA.
4.Whitney F Kellett, Kiril L Hristov,Xiangli Cui, andGeorgi V Petkov. SK and IK Ca2+-activated K+channels as novel pharmacological targets to control urinary bladder smooth muscle excitability and contractility.2008 Annual Experimental Biology meeting, (April 5-9, 2008), San Diego, CA, USA.(not sure)
5.Georgi VPetkov,Xiangli Cui,Krill Hristov, and Erric Rovner. (2007b). Electrophysiological and pharmacological evidence for the presence of the large conductance voltage- and Ca2+-activated K+(BK) channels in human urinary bladder smooth muscleL Potential physiological role. FASEB Summer Research Conference "Ion Channel Regulation" (Snomass Village, CO).
6. Sean Brown,Xiangli Cui,Kiril LHristov, andGeorgi VPetkov, G. (2007). Inhibitory mechanism of BRL37344, a specific β3-adrenoceptor agonist, on guinea pig and rat urinary bladder smooth muscle contractions: Role of the BK channel. 2007 FASEB Journal – Late-Breaking Abstracts. Abstract LB480 (2007 Experimental Biology Meeting, Washington, D.C., April 28-May 2, 2007).
中文論文：
1.趙倩倩， 景佳妮， 李海清， 劉 蓉， 李曉鵬，崔香麗*.β3 -AR 阻斷劑 SR59230A 對大鼠胸主動脈張力及microRNA 表達的影響.中國應用生理學雜志. 2017, 33（1）：6-10.
2.楊嵐， 李海清， 李曉鵬， 趙倩倩， 吳博威，崔香麗*.β 3-腎上腺素能受體通過降低鈣敏感性介導正常和心衰大鼠心臟的負性肌力作用.中國心血管病研究. 2015. 13:659-664
3.李曉鵬， 趙倩倩，楊嵐， 李海清，崔香麗*.β 3-腎上腺素能受體對大鼠主動脈平滑肌舒縮活動的影響及其機制. 中國應用生理學雜志. 2016， 32（1）：69-73
4.李海清，劉蓉，趙倩倩，楊嵐，景佳妮，崔香麗*.人參炔醇對大鼠心功能的影響。中國醫學創新. 2016.13（17）（總第 371 期）：1-6
5.崔香麗，高應，等. 吸煙對大鼠生長發育、細胞免疫及血清唾液酸含量的影響. 1994,25:
322-324
6.崔香麗，高應，等. 被動吸煙對大鼠的影響. 中國公共衛生學報. 1994；13: 13：246-247
7.崔香麗，雷玲，等. 吸入甲醛在大鼠體內的分布及其對還原型谷胱甘肽的影響. 中華預防醫學雜志. 1996；30：186
8.雷玲，崔香麗，等.吸入甲醛對大鼠肺的損傷作用. 中國公共衛生學報. 1996, 15: 234-235
9. 程牛亮，王惠珍，崔香麗，等. 香煙煙霧對大鼠晶狀體脂質過氧化與抗氧化作用的影響. 衛生研究. 1997, 26: 188-189
10.程牛亮，王惠珍，崔香麗，等. 香煙煙霧對大鼠晶狀體脂質過氧化與抗氧化作用的影響.微量元素與健康. 1997. 14: 4-6
11.陳還珍，崔香麗, 等. 心先安對大鼠肥厚心肌的作用. c7c7.app學報. 2002，33：208-209.
12.崔香麗，周尚忠，吳博威. 離子影像系統測定分離的單個心肌細胞鈣瞬變和收縮. c7c7.app學報. 2002；33：461-463
13.陳還珍，崔香麗, 等.MCI-154對離體大鼠心功能效應的影響. 中西醫結合心腦血管病雜志. 2004, 2: 467-469
14.黃文，孟華千，崔香麗,等. 香煙煙霧對大鼠血清SOD、MDA和GSHPx水平的影響及硒強化沙棘油的保護作用. c7c7.app學報. 2004, 35: 350-352
15.牛栓成，張軒萍，梁宏亮，崔香麗，等. 大鼠心肌細胞急性分離方法. c7c7.app學報. 2002，33：173-174
16.孟華千, 崔香麗. 環境污染對基因的影響. 醫學與哲學. 2004,25:51~52.
17.孟華千,崔香麗, 劉磊, 吳博威. 氨甲酰膽堿與去甲腎上腺素對心室肌細胞鈉鈣交換電流的聯合作用. 中國病理生理雜志. 2006; 22:159,
18.孟華千,崔香麗, 等. 氨甲酰膽堿與去甲腎上腺素對心室肌細胞L型鈣電流的聯合作用. c7c7.app學報. 2005, 36: 5-6
會議摘要：
1. 血漿中新型安眠鎮靜藥Zopiclone的薄層色譜分析. 王玉瑾,崔香麗. 1996.第五次全國法醫學術交流會. 第五次全國法醫學術交流會論文集.
2. 氨甲酰膽堿對大鼠心肌細胞的正性肌力作用及其可能機制. 2002. 崔香麗，吳博威. 中國生理學會第21屆全國代表大會暨學術會議. 中國生理學會第21屆全國代表大會暨學術會議論文摘要匯編 , Proceedings of 21 Chinese Physiological Conference
3. 氨甲酰膽堿對豚鼠心肌細胞正性肌力作用的可能機制. 2004. 崔香麗，吳博威. 國際心臟研究會中國分會第八屆學術會議暨中國病理生理學會心血管專業委員會第十一屆學術會議. 國際心臟研究會中國分會第八屆學術會議暨中國病理生理學會心血管專業委員會第十一屆學術會議論文摘要集.
4. Resveratrol protects epithelium cells from DNA damage through expression
of miR-16. ICPS2016-3-023.通信作者，第一作者：崔香麗
5. Role ofβ3 adrenoceptor in rat thoracic aorta contractility and the mechanisms underlying it. ICPS2016-4-062.通信作者：崔香麗
發表的著作：
1.職業病醫師培訓教材.人民日報出版社.2004年3月. 北京. (Chapter 1,編委)
2.心血管生理學與臨床. 高等教育出版社, 2004年3月。（編委）
3．醫學化學水平測試題集。1994年4月。黑龍江科技出版社。(Chapter 14,參編)
4.心血管生理學基礎與臨床. 高等教育出版社。2011.1.北京。 （第一篇，Chapter 19）朱妙章 唐朝樞等
