姓名：寧俊婭
性別：女
出生年月：1992.04
政治面貌：中共黨員
所在院系：c7c7.app基礎(chǔ)醫(yī)學(xué)院生理學(xué)系
學(xué)習(xí)工作經(jīng)歷
2015.09-2020.07山東大學(xué)，細胞生物學(xué)專業(yè)，理學(xué)博士
2020.09至今c7c7.app，講師
研究方向
惡性腫瘤的發(fā)生發(fā)展與抗腫瘤藥物的耐藥性機制研究
發(fā)表論文及其他科研學(xué)術(shù)成果
1.Junya Ning, Zhaomin Lin, Xuan Zhao, Baoxiang Zhao*, Junying Miao*. Inhibiting lysine 353 oxidation of GRP78 by a hypochlorous probe targeting endoplasmic reticulum promotes autophagy in cancer cells. Cell Death and Disease, 2019, 10(11):858. IF 2019: 6.304
2. Shi-Li Shen#,Jun-Ya Ning#, Xiao-Fan Zhang, Jun-Ying Miao, Bao-Xiang Zhao*.Through-bond energy transfer-based ratiometric fluorescent probe for the imaging of HOCl in living cells. Sensors and Actuators B: Chemical, 2017, 244:907-913. IF 2019: 7.100
3. Li-Jie Zhang#,Jun-Ya Ning#, Jun-Ying Miao, Jin-Ting Liu*, Bao-Xiang Zhao*. A new ratiometric fluorescent probe for detecting endogenous HClO in living cells. New Journal of Chemistry, 2018, 42(4):2989.
4. Qun Wei,Jun-Ya Ning, Xi Dai, Yuan-Di Gao, Le Su, Bao-Xiang Zhao*, Jun-Ying Miao*. Discovery of novel HSP90 inhibitors that induced apoptosis and impaired autophagic flux in A549 lung cancer cells. European Journal of Medicinal Chemistry, 2018, 145:551-558.
5. Wei Wang, Jun-Ya Ning, Jin-Ting Liu, Jun-Ying Miao, Bao-Xiang Zhao*. A mitochondria-targeted ratiometric fluorescence sensor for the detection of hypochlorite in living cells. Dyes and Pigments, 2019, 171:107708.
6. Huang M F, Chen L N,Ning J Y, et al. A new lipid droplets-targeted fluorescence probe for specific detection of SO2, derivatives in living cells [J]. Sensors and Actuators B: Chemical, 2018, 261:196-202.
7.He X, Lin Z,Ning J, Li N, Cui X, Zhao B, Hong F, Miao J. Promoting TTC4 and HSP70 interaction and translocation of annexin A7 to lysosome inhibits apoptosis in vascular endothelial cells. FASEB J. 2020 Sep;34(9):12932-12945.
苗俊英、趙寶祥、張尚立、寧俊婭;1，3，3-三甲基-2-苯并咪唑并吡啶乙烯基吲哚鎓碘化物在制備抗癌藥物中的應(yīng)用, 2019-04-12,中國, ZL201910294320.5.
科研項目
1.國家自然科學(xué)基金面上項目，31870831，膜聯(lián)蛋白A7與葡萄糖調(diào)節(jié)蛋白94關(guān)聯(lián)脂滴和細胞自噬的分子機制研究，2019/01-2022/12，在研，參與
2.國家自然科學(xué)基金面上項目，31871407，酯酶D調(diào)控其相互作用蛋白JAB1的去乙酰化及功能的機制研究，2019/01-2022/12，在研，參與
